In Events:
April 22nd 0296 | | St Gaius ends his reign as Catholic Pope
| April 22nd 0536 | | St Agapitus I ends his reign as Catholic Pope
| April 22nd 1056 | | Supernova Crab nebula last seen by the naked eye
| April 22nd 1073 | | Pope Alexander II buried/Ildebrando chosen as Pope Gregory VII
| April 22nd 1145 | | 19th recorded perihelion passage of Halley's Comet
| April 22nd 1164 | | Raynald of Dassel names Guido di Crema as anti-pope Paschalis III
| April 22nd 1370 | | Bastille begins being built in Paris
| April 22nd 1500 | | Pedro Alvarez Cabral discovers Brazil & claims it for Portugal
| April 22nd 1509 | | Henry VIII ascended to throne of England
| April 22nd 1521 | | French king Fran‡ois I declares war on Spain
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In Births:
April 22nd 1357 | | Johan I, King of Portugal (1383-1433)
| April 22nd 1357 | | Johan I, King of Portugal (1383-1433)
| April 22nd 1357 | | Johan I, King of Portugal (1383-1433)
| April 22nd 1451 | | Isabella I, of Castile, Queen of Spain (1479-1504), patron of Columbus
| April 22nd 1451 | | Isabella I, of Castile, Queen of Spain (1479-1504), patron of Columbus
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In Deaths:
April 22nd 0536 | | Agapitus I, Italian Pope (535-36), dies
| April 22nd 1253 | | Elias van Cortona, Italian general (1232-39), dies at about 53
| April 22nd 1355 | | Eleonora Plantagenet, daughter of King Edward II, dies at 36
| April 22nd 1462 | | Gilbert of Lannoy, master of Villerval/Tronchiennes/Santes, dies
| April 22nd 1521 | | Juan de Padilla, Spanish nobleman/communero-rebel, beheaded
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